New research led by academics at the University of Bristol Veterinary and Medical Schools used the 'One Health' approach to study three bacterial species in the noses of young cattle and found the carriage of the bacteria was surprisingly different. The findings which combined ideas and methods from both animal and human health research could help prevent and control respiratory diseases.
Cattle, like humans, harbour a wide range of bacteria in their noses, microbes which are normally present and probably necessary for health like those that live in the gut. However, some species of these bacteria do cause serious illness at times, particularly when infection becomes established in the lower respiratory tract within the lungs.
In an open access paper published in Scientific Reports today [Friday 16 August], the researchers investigated the patterns of acquiring and clearing these microbes in healthy young cattle, which have not previously been studied in detail.
The research team took nasal swabs at intervals during the first year of life, to detect their presence and measure their abundance using a DNA-detection technique called quantitative polymerase chain reaction (qPCR) that targeted genes found in three bacterial species well-known for their ability to cause respiratory disease in cattle: Histophilus somni, Mannheimia haemolytica and Pasteurella multocida.
The researchers found the carriage patterns of the three bacteria differed remarkably. Pasteurella was found in most of the animals, large numbers of bacteria were usually present, and the bacteria stayed in the nose for weeks or months. Histophilus was present in up to half the animals, usually in smaller numbers and the periods it was present were shorter. Mannheimia was rarely found although the numbers detected, when present, varied widely.
These differences are of interest because the numbers of bacteria and their duration of carriage are likely to influence their spread among healthy cattle and the likelihood of causing severe respiratory disease.
...follow the link to read the article in full on the University of Bristol website...