Model predicts vaccine effectiveness in animals

Friday, September 6, 2019
University of Edinburgh

A new epidemiological model predicts the effectiveness of vaccines in preventing or eliminating infectious diseases in livestock.

Scientists at the Roslin Institute have developed a new epidemiological model to investigate the effectiveness of vaccines for preventing, mitigating or eliminating infectious diseases in livestock.

When appropriately applied, even imperfect vaccines can prevent, eliminate or largely reduce the prevalence of viruses, the model shows.

The study has practical implications for the design of vaccines and vaccination programmes in livestock.

Multiplicative effect

The goal of effective vaccination is not only to protect individuals from disease, but to decrease the risk and severity of disease outbreaks, and ultimately eradicate the disease.

The model shows that combining diverse vaccine properties may have a multiplicative effect and thus be considerably more effective.

This could be used to prevent outbreaks if the vaccine is applied as a preventive measure, or to eliminate disease spread if applied during outbreaks.

...follow the link to read the article in full on the University of Edinburgh website...